Abstract
Fatty acid synthase enzyme (FASN - fatty acid synthase, EC 2.3.1.85) is responsible for the endogenous synthesis of long chain fatty acids by performing condensation reactions of the precursors acetyl-CoA and malonyl-CoA. FASN complex is formed by seven catalytic domains [²-ketoacyl synthase (KS), acetyl-CoA transacylases e malonyl-CoA transacylases (MAT), dehydratase (DH), enoyl reductas…