Juliana Ronchi Corrêa in research grants and scholarships supported by FAPESP.
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Acute lymphocytic leukemia (ALL) is the most common type of cancer in childhood. Eighty five percent of ALL originate from B-cell precursors (B-ALL) and 15% from thymocytes (T-ALL). Different chromosomal alterations and oncogenic mutations are known to interrupt the normal process of cell differentiation and/or induce proliferation. We have recently described oncogenic mutations in the IL…
The oncogenic IL7R is known to activate three pathways in acute lymphoid leukemia (ALL): JAK/STAT, PI3K/AKT/mTOR and RAS/MEK/ERK. However, the activation of RAS/MEK/ERK has not been characterized. Mutations in RAS/MEK/ERK are recurrent in human ALL (7/15 cases of ALL with mutations in the IL7R have cooccurring mutations in genes of the RAS/MEK/ERK pathway) and in murine ALL originating fr…
| 1 / 1 | Completed scholarships in Brazil |
| 1 / 1 | Completed scholarships abroad |
| 2 / 2 | All Scholarships |
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