Graduated in Biomedical Sciences from the Universidade de São Paulo (2018), I conduct research in health sciences, focusing on the development of new therapies for cancer treatment.Currently, I am a PhD candidate at the Universidade de São Paulo, working at the Laboratório de Biologia Molecular e Biotecnologia Industrial de Microrganismos (LABIMBIM). (Source: Lattes Curriculum)
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Melanoma is an aggressive skin neoplasm with high plasticity, drug resistance and a propensity to metastasize. 50% of patients with this disease have a mutation in the BRAF protein kinase, which results in exacerbated activation of the MAPK pathway. Patients with this mutation are eligible to be treated with MAPK inhibitors, but may exhibit drug resistance and increased tumor invasiveness…
Melanoma is a malignant skin neoplasm with high plasticity, chemoresistance, and propensity to metastasis. A significant percentage of patients with this disease have BRAFV600E mutation and can be treated with Vemurafenib. Although this drug has an effective initial response, a significant number of patients have tumor resistance and disease progression after a short period of treatment i…
A significant number of patients with acute leukemia of lymphocytic (ALL), malignant cells have a metabolic defect in the synthesis of asparagine (Asn), depending on an exogenous source of this amino acid to survive. The enzyme L-asparaginase is used in the treatment of this disease in order to exhaust the stocks of asparagine in the bloodstream required for tumor cells. Although this enz…
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CV Lattes
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