Abstract
In order to destroy invading pathogens, activated neutrophils generate reactive oxygen speciesand extracellular DNA networks associated with histones and myeloperoxidase (MPO), forming a trap to facilitate killing of the infectious agent. These networks were discovered in 2004, and called "NETs" (Neutrophil Extracellular Traps), with the neutrophil-triggered process named NETosis. The NET…