Abstract
Chagas disease caused by the protozoan parasite Trypanosoma cruzi is considered an important health problem in South America. In the mammalian host, intra-cellular amastigotes forms of T. cruzi are target of the cell mediated immune response. IFN-gama producing CD4 and CD8 T cells recognize epitopes of amastigotes and are important for the host resistance.Due to its capacity to activate I…