BSc in Pharmaceutical Biochemistry from the Sao Paulo State University (UNESP), Brazil. Worked as an undergrad research assistant in the Laboratory of Basic Immunology at the Faculty of Pharmaceutical Sciences (2015-2019). MSc in Immunology from the University of Campinas (UNICAMP), Brazil (2019-2021). Visiting Researcher at the Immunology Department at the University of Colorado - Anschutz Medical Campus (2022-2023). Currently working as a Ph.D. Student of Immunology at the Weill Cornell Graduate School. Expertise in Cellular Immunology and Immunometabolism, with emphasis on metabolic adaptations of tissue-resident macrophages during phagocytosis of apoptotic cells (efferocytosis). (Source: Lattes Curriculum)
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Immune cells are dynamic and respond to foreign antigens and tolerate self-antigens requiring, a process that requires metabolic adaptation for survival, proliferation, and return to homeostasis. Fatty acids regulate several metabolic and signaling pathways, including insulin signaling, calcium flux, and inflammation. Exposure of macrophages to saturated fatty acids or LPS activates pathw…
The phagocytosis of apoptotic cells (ACs) - called efferocytosis - is an essential process in the maintenance of tissue homeostasis. Macrophages, which collaborate in the defense against microorganisms, also play an important role in ACs removal. Depending on the microenvironment and aggressor agents presented in the tissue, there are at least two macrophages populations that differ in ph…
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