Abstract
Replication Protein A (RPA), the main single-stranded DNA ligand of eukaryotes, is a heterotrimeric complex formed by three subunits (RPA-1, RPA2 and RPA-3) and participates in several fundamental processes such as replication, repair and signaling checkpoint. Our group found that, depending on the life form of the parasite, RPA is found in the nucleus (in replicative forms) or in the cyt…