Currently a Postdoctoral Fellow at the Laboratory of Neurobiology and Stem Cells at the Institute of Biomedical Sciences, University of São Paulo (ICB-USP), investigating protein trafficking and the role of the cellular prion protein and its ligands in the biology of glioblastoma stem-like cells. Holds a Ph.D. from the Systems Biology Program at ICB-USP. Graduated in Pharmacy and Biochemistry from the School of Pharmaceutical Sciences, University of São Paulo (FCF-USP)." (Source: Lattes Curriculum)
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Glioblastoma Multiforme (GBM) is a highly aggressive glial tumor, with a high recurrence and death rates. Recent studies indicate that the GBM is maintained by a subpopulation of cellswith stem-cell characteristics, denominated Glioblastoma Stem Cells (GSCs). Recently ourgroup has identified the Cellular Prion Protein as having an important role in the modulationof the GSCs undifferentiat…
The Glioblastoma Multiforme (GBM) is a highly aggressive glial tumor, with a high recurrence and death rates. Recent studies indicate that the GBM is maintained by a sub-population of cells with stem-cells characteristics, denominated Glioblastoma Stem Cells (GSCs). Recently our group has identified the Cellular Prion Protein as having an important role in the modulation of the GSCs undif…
Among all types of glioma, the most aggressive form (stage IV/IV) is Glioblastoma Multiforme (GMB), related to the lowest survival rate amongst patients. This type of tumor has a specific cell population called glioblastoma stem-cells (GSCs), which are essential to the proliferation, capability of invasion and also directly related to the low rates of the chemotherapy. Thus, the GSCs ris…
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