CV Lattes
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Universidade de São Paulo (USP). Faculdade de Ciências Farmacêuticas (FCF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Chemistry Technician (2013) from ETEC Cel. Fernando Febeliano da Costa. Bachelor's Degree in Chemistry Education (2014-2017) from the Federal Institute of Education, Science and Technology of São Paulo. Lavoisier Award (CRQ-IV) in 2018.During her undergraduate studies, participated in the Institutional Teaching Initiation Scholarship Program (PIBID, 2015-2016), developing pedagogical tools for teaching chemistry. Also carried out a scientific initiation project focused on synthetic studies aimed at the alkaloid Prebalamide (2017). Holds a Direct Ph.D. (2023) in organic synthesis from the Institute of Chemistry at the University of São Paulo (USP), developing the project Application of haloperoxidase in a continuous flow system for selective reactions (FAPESP) and photoinduced radical methodologies for the synthesis of heterocycles, under the supervision of Prof. Dr. Leandro Helgueira. Currently pursuing a postdoctoral fellowship (2023-present) at the School of Pharmaceutical Sciences, USP, working on the development of carbonylative coupling reactions and palladium-catalyzed cascade cyclizations (FAPESP), under the supervision of Prof. Dr. Hélio Stefani. Also completed a postdoctoral fellowship (2024-2025) at the Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA), under the supervision of Prof. Gary Molander and Dr. Eugénie Romero, focusing on the development of metallaphotoredox reactions for the cyclization of glycals and photoinduced radical functionalization of biomolecules. (Source: Lattes Curriculum)
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The project has as its main focus the use of 1- and 2- iodoglucal in transformations involving carbonylative coupling reactions and cyclization reactions. It is also intended, whenever possible, to evaluate the biological activity of the prepared compounds (antifungal, anticancer and anti-inflammatory activity).
The use of vanadium-dependent haloperoxidases has presented several challenges when it comes to selectivity, the most challenging being the high reactivity of the halogenated species generated by the enzyme. Another challenge is the inactivation of the enzyme through the oxidizing agent, when it is in excess, or in prolonged contact with the enzyme. It is believed that the use of a reacto…
Glycosides are renewable building blocks ubiquitous in nature and widely explored in organic synthesis and medicinal chemistry. C-Glycosides exhibit in their structures an aglycone moiety or another glycoside linked through a C-C bond, which confers enzymatic and chemical resistance to hydrolysis. There are pharmaceutically relevant glycosides that exhibit a spirocyclic structure. Spiro c…
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