Abstract
Trypanosoma cruzi is the causative agent of Chagas disease, identified in 1909 by Carlos Ribeiro Justiniano das Chagas, and remains a public health concern in Brazil to this day. Classified as a neglected disease by the World Health Organization, its treatment is limited to two drugs, benznidazole and nifurtimox, which were introduced in the 1960s. These drugs, however, cause severe side …