Graduated in Biological Sciences from Anhembi Morumbi University. She is currently a PhD student at the Laboratory of Investigation of Cellular Responses to DNA Damage at the Department of Biochemistry and Molecular Biology at UNIFESP. (Source: Lattes Curriculum)
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The DNA Damage Response (DDR) contribute to genomic stability through the modulation of a myriad of cellular pathways that are responsible to detect DNA lesions, promote DNA Damage signaling and active DNA repair and DNA damage tolerance mechanisms. Besides that, it also modulates another cellular responses such as protein homeostasis and metabolism of biomolecules such as carbohydrates a…
The DNA Damage Response (DDR) is a complex network of biological processes that are activated in response to damages in the DNA molecule, thus preventing genomic instability. The DDR regulates proteins involved in biologic processes such as DNA replication and repair, cell cycle e mitosis being conserved from yeast to humans. Recently, it has been growing evidences suggesting that during …
Inositol pyrophosphates are energy-rich signaling molecules derived from inositol conserved from yeast to humans. They regulate and control cellular homeostasis by modulating cellular responses through interactions with target proteins via two distinct mechanisms: i) allosteric interactions with protein domains such as PH (Pleckstrin Homology) domains, and ii) non-enzymatic pyrophosphoryl…
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