Abstract
Peripheral insulin resistance (RI) and type 2 Diabetes mellitus (DM2) have a high prevalence in obese patients. However, there is an elevated number of non-obese patients that have DM2. The causes associated with the development of DM2 and the characterization of the immunological response in these cases are not clear. Goto-Kakizaki (GK) rats develop genetically well defined condition of …