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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biomedicine from the Federal University of Rio Grande do Sul (UFRGS) and Master and Doctor in Biological Sciences: Biochemistry, from UFRGS. She is currently a FAPESP postdoctoral fellow, developing her project at the Institute of Biomedical Sciences of the University of São Paulo (ICB-USP). Her research aims to unravel the role of cellular prion protein (PrPC) in Notch and WNT signaling in glioblastoma stem cells, through PrPC deletion by Crispr/Cas9. (Source: Lattes Curriculum)
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Among all tumors of the Central Nervous System (CNS), Glioblastoma Multiforme (GBM) is the most aggressive and resistant to standard treatments. Despite many studies, the mean survival of patients is only 15 months. Within the tumor mass, there are groups of cells that have features of stem/progenitor cells, named glioblastoma stem cells (GSCs) and possess large potential for proliferatio…
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