Abstract
Recently with the discovery of the structure of fungal luciferin it became possible to know a secondary pathway for the expression of bioluminescence called Caffeic Acid Cycle (CAC). Caffeic acid, generated in fungi from tyrosine in the Shikiimate pathway is the initial substrate for the formation of hispidin by the enzyme complex hispidin synthase (HispS). Hydroxylation of hispidin by a …