Abstract
In the present project we intend to evaluate experimentally by means of 1H, 13C and 19F NMR spectroscopies in situ, in the reaction flask itself, using NMR and infrared benchtop spectrometers, which are being requested in the current FAPESP Young Researcher Project, and by theoretical calculations of electronic structure, the Thorpe-Ingold effect and the mechanisms and rates of lactonizat…