Abstract
The renin-angiotensin system (RAS) is involved in physiological and pathological processes. Nowadays, a new paradigm has emerged in which it is believed that two central axes modulate the function of the RAS: a deleterious axis composed of ACE/Ang II/AT1 receptor and another beneficial axis formed of ACE2/ Ang 1-7/MAS receptor. These functional aspects multiply the possible treatment targ…