CV Lattes
ORCID
Abstract
Autosomal dominant polycystic kidney disease (ADPKD) is a common hereditary disorder characterized by the formation of cysts in the renal parenchyma. Cystic expansion leads to compression of adjacent nephrons, as well as an inflammatory process that results in progression to renal fibrosis, with increasing loss of nephrons, culminating in decreased renal function and leading patients to d…