Abstract
The increase in PRC2/EZH2 Polycom complex activity in aggressive cancer induces gene silencing through histone modifications and chromatin accessibility. However, the mechanism underlying the targeting of PRC2/EZH2 to specific regions of the genome is under investigation. In this context, long noncoding RNAs emerge as potential mediators as they can recruit and Interact with PRC2/EZH2. Cl…