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Analysis and classification of X-2 chromosomal translocations in Drosophila melanogaster

Grant number: 20/05086-4
Support type:Scholarships in Brazil - Scientific Initiation
Effective date (Start): August 01, 2020
Effective date (End): December 31, 2021
Field of knowledge:Biological Sciences - Genetics - Animal Genetics
Principal researcher:Maria Dulcetti Vibranovski
Grantee:Amanda Luvisotto Gomes Leite Silva
Home Institution: Instituto de Biociências (IB). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:15/20844-4 - The role of gametogenesis on the origin and evolution of new genes, AP.JP

Abstract

Translocations between the X chromosome and autosomes are one of the greatest causes of male infertility in drosophilidae. The reason why this occur may be related with differences on the regulation and the pattern of condensation of these chromosomes so that this translocations place the chromosomes in question under asynchronous control during a important period of spermatogenesis. This project pursuit, through cytogenetic analysis, to explore the differences between the translocations found in 9 lines of Drosophila melanogaster carriers of X-2 translocations, investigating the distinctions among these translocations to obtain information about the sort of the events leading to sterility in the male of the specie. (AU)

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