Abstract
Trypanosoma cruzi is the parasite that causes Chagas disease. Recently it was proposed that its genome is organized in two compartments: the central compartment - composed of highly conserved genes, and the disruptive compartment - composed of rapidly evolving genes, such as trans-sialidase, mucins and MASP virulence genes. Our group showed enrichment of histone H2B variant (H2B.V), a mar…