CV Lattes
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Universidade Estadual de Campinas (UNICAMP). Instituto de Biologia (IB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has experience in Biochemistry, focusing on Molecular Biology (Source: Lattes Curriculum)
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Melanoma is defined as an aggressive type of cancer due to its high ability to develop metastases and low response to therapy. In recent decades its incidence has been increasing and by 2040, estimates predict an increase of 50% in the number of cases and 68% in the number of deaths. Usually the melanoma studies are based on 2D cell culture, however this model is not able to mimic importa…
Melanoma is the most lethal type of skin cancer due to its high proliferative rate and capacity for metastasis. Additionally, this tumor displays low response to treatment, which in part is due to a high basal rate of autophagic flow. Therefore, the study of these cellular mechanisms and for the screening of compounds, the 3D culture models have been shown to be effective, as it allows gr…
One of the main challenges in targeted therapy and immunotherapy is the poor treatmentresponse, attributed to biochemical and physical barriers that protect tumor cells, enablingtheir continuous adaptation and survival. Among these barriers, the crosstalk between thetumor-associated extracellular matrix and hypoxia is crucial to inactivating immune systemcells, antitumoral compounds, and …
| 1 / 1 | Ongoing scholarships in Brazil |
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| 1 / 1 | Completed scholarships abroad |
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