CV Lattes
ORCID
Abstract
Limb-Girdle Muscular Dystrophy 2B (LGMD2B) is caused by pathogenic mutations in the gene that codes for dysferlin, a protein that acts in muscle regeneration and membrane repair. Previous studies carried out by our group using human myoblasts from a LGMD2B patient showed a loss in the differentiation of myoblasts to myotubes by the formation of smaller myotubes and containing fewer nuclei…