CV Lattes
ORCID
Abstract
Cardiorenal Syndrome (CRS) is defined as an acute or chronic dysfunction of the heart and kidneys, in which injury to one organ causes disturbances in the other. The vascular system is also affected by this syndrome through hemodynamic, mechanical, biochemical, neurohumoral, and protein-bound uremic toxins. The purinergic system exerts its signaling through extracellular nucleotides and n…