Abstract
The exosome complex is one of the most versatile RNA degradation machineries ineukaryotes. It plays an important role in the biogenesis of various RNAs (rRNAs, snoRNAs, snRNAs, ncRNAs) and in the regulation of specific mRNA expression. levels both in the nucleus and cytoplasm. The exosome acts at various stages ofRNA processing and degradation and has 3'-5' exoribonucleolytic acti…