Abstract
We have previously demonstrated that iNOS knockout animals show deficits in the extinction of contextually conditioned fear (Lisboa et al., 2015 doi: 10.1093/ijnp/pyv005). We also saw that this behavior could result from a compensatory increase in NO production in the medial prefrontal cortex (mPFC) of these animals, but not in the hippocampus, via nNOS, since the inhibition of this isofo…