Has experience in Chemistry, focusing on Organic Synthesis, acting on the following subjects: zika virus, ns3 helicase, hydantoin, oxadiazole and enzymatic inhibitors. (Source: Lattes Curriculum)
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Approximately 60% of small-molecule drugs contain nitrogen heterocycles in their molecular frameworks. Among the N-heterocycles, pyrrolo[2,1-a]isoquinolines and 2-pyrrolo[2,3-b]indoles stand out. Recently, our group reported a one-pot copper(II)-catalyzed conjugate addition/cyclization cascade method for the synthesis of phenylpyrrolo[1,2-a]isoquinolines. These compounds were evaluated ag…
The Zika virus, emerging in Brazil since 2015, is transmitted mainly via the bite of female Aedes aegypti mosquitoes and usually causes mild symptoms. However, there are other clinical manifestations of the disease such as the triggering of neurological problems that demonstrate the need for the development of antivirals as more effective therapeutic approaches. Therefore, a high-throughp…
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CV Lattes
ORCID