Abstract
Long non-coding RNAs (lncRNA) constitute a class of RNAs with function in the regulation of gene expression and cell signaling. Several lncRNAs play roles in cancer and one of them, RMEL3 (Restricted to Melanoma 3), was identified by our laboratory in melanoma, a cancer originated from melanocytes, pigment cells of the skin. RMEL3 is overexpressed in melanomas carrying the BRAFV600E mutat…