Abstract
Gliomas are brain tumors with low therapeutic response, heterogeneous and classified by histopathological characteristics and some molecular markers. In them, mutation in the gene isocitrate dehydrogenase 1 and 2 (IDH1/1DH2) can occur, which defines a different type of glioblastoma that has hypermethylation in the CpG islands, a phenotype known as G-CIMP, and it has a favorable prognosis …