Abstract
The lymphoid leukemias are hematologic neoplasms in the B and T lineages and are the major cause of infant death caused by cancer. About 10% of the ALL-T and 2% of the ALL-B present a leukemogenic mechanism caused by activating mutations in the gene encoding the hIL7R± protein (± chain of the human 7 interleukin receptor). The IL7R± is a protein expressed on the lymphocyte surfaces, it is…