Master's student in Genetics and Molecular Biology at the Masters Program of the Institute of Biology at Unicamp. Graduated in Biological Sciences from the State University of Campinas - Unicamp. Currently carrying out a Master's project at the Boldrini Research Center named "Transcriptional memory and drug resistance in pediatric Acute Lymphoblastic Leukemia" under the supervision of Prof. Dr. José Andrés Yunes and with the support of CNPq. The research focuses on human genetics and oncology, with the development of patient-derived xenografts and ex vivo drug screeningTranslated with DeepL.com (free version) (Source: Lattes Curriculum)
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Acute lymphoid leukemia (ALL) is the main cancer affecting children. Despite the high cure rates achieved in recent decades, and even with great effort in the search for new therapeutic strategies, approximately 20 to 30% of cases relapse from the disease, due to resistance to chemotherapy. Although some genetic subgroups of ALL are associated with a peculiar drug resistance/sensitivity p…
Pitt-Hopkins Syndrome (PTHS) is a rare genetic disorder, belonging to the group of autism spectrum disorders (ASD), caused by mutations in the TCF4 gene. This encodes the protein 'Transcription Factor 4', whose role is to coordinate cell proliferation and differentiation of neural progenitor cells. The different de novo mutations that occur in PTHS patients result in haploinsufficiency of…
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