Abstract
Amyotrophic Lateral Sclerosis (ALS) is an incurable and progressive neurodegenerative disease impacting motor neurons, leading to bulbar dysfunction in over 80% of cases. Survival rates after diagnosis vary from 20 to 48 months, with only 5 to 10% of patients living beyond 10 years, underscoring the critical need for early detection. However, the absence of reliable clinicopathological ma…