Abstract
The Endocannabinoid System constitutes a complex set of pathways signaling whose functions range from presynaptic neuronal inhibition to immunomodulation. The endogenous messengers of the system are lipids synthesized on demand (anandamide and 2-arachidonoyl glycerol) that interact with G protein-coupled receptors (CB1 and CB2). CB1 receptors arefound primarily in the central nervous syst…