Abstract
PIMREG (PICALM interacting mitotic regulator) is a nuclear protein enriched in the nucleolus and highly expressed in the thymus and in the spleen. Besides that, it is a substrate of the anaphase/cyclosome promoter complex (APC/C), playing a role as a mitotic regulator. Also, PIMREG function is related to carcinogenesis, since its expression is increased in several types of cancer, especia…