Has experience in Chemistry, focusing on Chemistry (Source: Lattes Curriculum)
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The processing of ribosomal RNA occurs through meticulous maturation steps coordinated by protein cofactors and ribonucleoproteins, which act from the nucleolus until the complete maturation of rRNA in the cytoplasm. In the final stages of 7S pre-rRNA processing, the Nop53 protein recruits the exosome complex for the processing of the 3' end of 7S pre-rRNA through the RNA helicase Mtr4, g…
The RNA exosome is a ribonucleolytic complex formed by the association of differentsubunits. Because of its exoribonuclease 3'à5' catalytic activity, the exosome controls thelevels of all classes of RNAs, regulating the chromatin structure, gene expression, celldifferentiation and ribosome biogenesis. In this context, this RNase has been the main focus ofresearch in our laboratory. The ex…
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CV Lattes
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