Abstract
Fibroblast Growth Factor 2 (FGF-2 or bFGF) is a prototype derivative of the FGF family, which in turn is involved in tumor expansion and development. In the literature, there are several reports of its involvement with melanoma, due to its high expression by malignant cells, disease progression and poor prognosis. On the other hand, an anti-FGF-2 monoclonal antibody (mAb) named 3F12E7, de…