CV Lattes
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Universidade Estadual Paulista (UNESP). Campus de Botucatu. Instituto de Biociências (IBB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has experience in Morphology, focusing on Anatomy, acting on the following subjects: flavonoids therapy, gait analysis, mdx mice and pulmonar ventilation. (Source: Lattes Curriculum)
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In the absence of dystrophin, muscle fibers undergo membrane rupture, releasing damage-associated molecular patterns (DAMPs), which leads to elevated serum creatine kinase (CK) levels, inflammation (characterized by increased TNF-¿ levels), and ultimately functional loss. The mdx mouse model, which mimics Duchenne muscular dystrophy (DMD), presents muscle fibers lacking dystrophin, result…
Duchenne muscular dystrophy (DMD) is a severe, progressive, X-linked muscle disease caused by the loss of dystrophin. DMD is associated with muscle necrosis, degeneration, inflammation, fat replacement, and fibrosis, resulting in muscle weakness, cardiorespiratory failure, and premature death. There is no curative therapy. Investigations into disease mechanisms offer an opportunity to ide…
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