CV Lattes
ORCID
Abstract
Osteosarcoma is a primary bone tumor that can affect children and adolescents, and has an invasive profile with high rates of metastasis. The main therapeutic approach for osteosarcoma is surgical resection which, when metastatic, has a 5-year survival of less than 30%. O-GlcNacylation is a post-translational modification that consists of the incorporation of O-GlcNac (O-linked-²-N-acetyl…