Abstract
Acetaldehyde produced endogenously or by exogenous exposure is associated with several pathophysiological processes. Accumulation of endogenous aldehydes leads to genotoxicity. Aldehydes react with amine and thiol groups of proteins, nucleic acids and some lipids and promote changes in these biomolecules. Recently, a pathway for the production of acetaldehyde via ketoacid dehydrogenases, …