Abstract
Objective: This study aims to investigate tooth resorption resulting from endodontic infection, in the presence or absence of TNF-z receptor-1 (TNFR1). Methods: To evaluate the mechanisms involved in the process of tooth resorption, 10 C57BL/6 mice (Wild-type; wild) and 10 mice genetically deficient (knockout) of TNFR1 will be used. For induction of apical periodontitis, the animals will …