Abstract
MICA and MICB molecules are constitutively expressed in fibroblasts, monocytes and epithelialcells, however, their expression is stimulated in conditions such as cancer, infections andautoimmune diseases, acting as a marker of cellular stress. The MICA and MICB genes areencoded on chromosome 6 in the Major Histocompatibility Complex (MHC) region, the mostvariable region of the human genom…