Abstract
NAFLD represents a heterogeneous group of liver diseases that can range from simple steatosis (NAFL, accumulation of lipids exceeding 5 to 10% of liver mass), to more severe conditions such as steatohepatitis (NASH), cirrhosis and cellular hepatocarcinoma (HCC). In a preliminary study we found that the development of NAFL and progression to NASH induced by PTEN deletion in hepatocytes is …