graduation at Biomedicina from Universidade Federal de São Paulo (2023). (Source: Lattes Curriculum)
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The cell non-autonomous regulation of the proteostasis in peripheral tissue by neurons in animals has been known for at least a decade. However, only recently it was observed that glial cells can also promote this type of regulation. In Caenorhabditis elegans, the activation of stress pathways (UPRER/XBP-1, UPRMT/JMJD-1.2 and HSR/HSF-1) in CEPsh astrocyte-like glial cells can extend lifes…
With the increase in life expectancy, there is also an increase in the incidence of diseases linked to aging, two of which stand out are Diabetes Mellitus (DM) and Alzheimer's Disease (AD). Although both are complex diseases involving energy metabolism and the other affecting the central nervous system (CNS), the literature has pointed to possible connections between these conditions. Sin…
The central nervous system (CNS) coordinates a myriad of physiological functions in the body. Besides receiving signals from the environment to respond to infection, the CNS is also involved in the regulation of the immune system. In the CNS, glial cells can be as important as neurons, but the interaction between glia and the peripheral immune system in the model organism Caenorhabditis e…
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