Abstract
Medication-related osteonecrosis of the jaws (MRONJ) is a condition in which the patient exhibits jawbone exposure for more than 8 weeks due to the use of certain classes of medications, such as bisphosphonates and some monoclonal antibodies, without a prior history of head and neck radiotherapy. Bisphosphonates inhibit bone resorption by inducing apoptosis in osteoclasts, whereas denosum…