Abstract
NLRP3 is a cytoplasmic receptor that, when activated, forms a protein complex called inflammasome, consisting of NLRP3, caspase-1 and an adapter protein (ASC), and responsible for acting in the release of IL-1b and IL-18. Thus, the NLRP3 inflammasome participates in the pathogenesis of many diseases, including allergic reactions such as asthma, atopic dermatitis, rhinitis and allergic con…