CV Lattes
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ORCID
Universidade de São Paulo (USP). Faculdade de Medicina (FM) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Science from Centro Universitário Fundação Santo André (1986), graduated in Biology from Universidade Santa Cecilia dos Bandeirantes (1988), Master's degree in Molecular Biology from the Federal University of São Paulo (1998), Doctorate in Sciences in the area of Pathophysiology Experimental from the Faculty of Medicine of the University of São Paulo (2002) and Post-Doctorate from the Department of Clinical Medicine of the Faculty of Medicine of the University of São Paulo (2010). He is currently a Scientific Researcher, level VI at the Hospital das Clínicas of the University of São Paulo carrying out scientific research activities at the Lipid Laboratory (LIM 10) in lipid and lipoprotein metabolism and dyslipidemia. He has experience in biochemistry and chromatography. (Source: Lattes Curriculum)
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Familial hypercholesterolemia (FH) is an autosomal dominant genetic disorder characterized by very elevated LDL-c (low density lipoprotein cholesterol) plasma concentration and by increased risk of premature coronary artery disease which is caused by defects of the LDL receptor in hepatocytes and in cells such as fibroblasts that prevent the removal of LDL from the circulation. LDL partic…
The physiological oxidation of cholesterol results in oxysterols, which are transported by lipoproteins in the bloodstream to the liver where they act as a precursor of bile acids synthesis. Bile acids are secreted in the bile and feces. This transportation mechanism is inherent to the reverse cholesterol transport system where HDL-C plays an important role removing intracellular choleste…
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