Abstract
Acute lymphoblastic leukemia (ALL) is a type of malignant hematological neoplasm, frequent in children and characterized by overproduction of blasts in the bone marrow and extramedullary regions. Somatic mutations in exon 6 of the IL-7Ra gene are related to the leukemogenesis process and are expressed in approximately 9% of patients with T-ALL. Anti-IL7R murine monoclonal antibodies, call…