Abstract
The periapical lesion is an inflammatory response to infection in the root canal system.roots, with the participation of different cell types, receptors and ligands during theits development. Pathogen-associated molecular patterns (PAMPs) as well assynthetic ligands such as Pam3Cys, bind to toll-like receptors, such as TLR2,to activate the innate immune system. Regulatory T lymphocytes (T…