Abstract
Accidents caused by snakes of the genus Bothrops induce severe clinical manifestations such as local and systemic myonecrosis, renal dysfunction, hemorrhage, coagulopathy, and hypotension. The treatment for envenomation by Bothrops spp. is restricted to polyvalent serotherapy. B. alternatus (Urutu-Cruzeiro) venom exhibits peculiar neurotoxic action in rodent nerve-muscle preparation in vi…