CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biotechnology by the University of São Paulo (USP). PhD student in the postgraduate program in Microbiology at the Institute of Biomedical Sciences (ICB) at USP, under the supervision of Professor Robson Francisco de Souza. Has experience in analysis of comparative genomics, genomic context, molecular modeling, and Bioinformatics in general. Currently, is working in the field of Bioinformatics, developing his doctoral project titled "Study of the association of tailoring enzymes with secondary metabolite-producing enzymes, and the construction of predictors for products and biosynthetic loci," which focuses on the prediction and in silico characterization of BGCs (Biosynthetic Gene Clusters) and peptide natural products without experimental characterization. (Source: Lattes Curriculum)
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The demand for new bioactive compounds has been increasing significantly, driven by the growing need for more efficient antibiotics against super-resistant bacteria. In this context, peptide natural products are compounds with broad functional diversity that include both ribosomal peptides (RiPPs) and non-ribosomal peptides (NRPs), whose synthesis is independent of the translation machine…
Recently, it has been demonstrated that the fusion of the AMT domain with cytoplasmic domains, endowed with histidine-kinase activity, resulted in the loss of its transporter function, transforming into a specific sensor for external levels of ammonia/ammonium. This process plays a crucial role in nitrogen fixation conducted by microorganisms, proving essential in biogeochemical cycles an…
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