Abstract
Insulin resistance (IR) and inflammation accompany the development of type 2 diabetes mellitus (DM2), with a high prevalence in obese patients. However, a high percentage of non-obese individuals have DM2, especially in certain regions. For example, in Brazil, the percentage reaches 10% to 20%, while in Japan, around 60% of patients with DM2 are not obese. The causes associated with the d…